| 8/31/2019 | VMI (5-7) | 17 | at | Marshall | 56 | SoCon (1AA) | ||
| 9/6/2019 | Marshall | 7 | at | Boise State (12-2) | 14 | at MW | ||
| 9/14/2019 | Ohio (7-6) | 31 | at | Marshall | 33 | MAC | ||
| 9/28/2019 | Cincinnati (11-3) | 52 | at | Marshall | 14 | AAC | ||
| 10/5/2019 | Marshall | 13 | at | Middle Tenn State (4-8,3-5) | 24 | |||
| 10/12/2019 | Old Dominion (1-11,0-8) | 17 | at | Marshall | 31 | |||
| 10/18/2019 | Marshall | 36 | at | Florida Atlantic (11-3,8-1) | 31 | |||
| 10/26/2019 | Western Kentucky (9-4,6-2) | 23 | at | Marshall | 26 | |||
| 11/2/2019 | Marshall | 20 | at | Rice (3-9,3-5) | 7 | |||
| 11/15/2019 | Louisiana Tech (10-3,6-2) | 10 | at | Marshall | 31 | |||
| 11/23/2019 | Marshall | 13 | at | UNC-Charlotte (7-6,5-3) | 24 | |||
| 11/30/2019 | Florida Intl (6-7,3-5) | 27 | at | Marshall | 30 | |||
| 12/23/2019 | UCF (10-3) | 48 | vs | Marshall | 25 | Gasparilla Bowl - Tampa FL | AAC |
| vs Marshall | vs Other Opponents | Marshall compared to OOs | |
| Record: | 5-8 | 91-64 | |
| Points Scored: | 25.00 | 30.17 | 5.17 |
| Points Allowed: | 25.77 | 25.95 | -0.18 |
| Margin: | -0.77 | 4.22 | 4.99 |
| Total Points: | 50.77 | 56.12 | -5.35 |