| 8/31/2019 | Norfolk State (5-7) | 21 | at | Old Dominion | 24 | MEAC (1AA) | ||
| 9/7/2019 | Old Dominion | 17 | at | Virginia Tech (8-5) | 31 | at ACC | ||
| 9/21/2019 | Old Dominion | 17 | at | Virginia (9-5) | 28 | at ACC | ||
| 9/28/2019 | East Carolina (4-8) | 24 | at | Old Dominion | 21 | AAC | ||
| 10/5/2019 | Western Kentucky (9-4,6-2) | 20 | at | Old Dominion | 3 | |||
| 10/12/2019 | Old Dominion | 17 | at | Marshall (8-5,6-2) | 31 | |||
| 10/19/2019 | Old Dominion | 14 | at | UAB (9-5,6-3) | 38 | |||
| 10/26/2019 | Florida Atlantic (11-3,8-1) | 41 | at | Old Dominion | 3 | |||
| 11/2/2019 | Old Dominion | 17 | at | Florida Intl (6-7,3-5) | 24 | |||
| 11/9/2019 | Texas-San Antonio (4-8,3-5) | 24 | at | Old Dominion | 23 | |||
| 11/23/2019 | Old Dominion | 17 | at | Middle Tenn State (4-8,3-5) | 38 | |||
| 11/30/2019 | UNC-Charlotte (7-6,5-3) | 38 | at | Old Dominion | 22 |
| vs Old Dominion | vs Other Opponents | Old Dominion compared to OOs | |
| Record: | 11-1 | 73-70 | |
| Points Scored: | 29.83 | 27.63 | -2.20 |
| Points Allowed: | 16.25 | 28.01 | -11.76 |
| Margin: | 13.58 | -0.38 | -13.96 |
| Total Points: | 46.08 | 55.64 | -9.56 |