| 9/1/2018 | Texas-Permian Basin | 16 | at | Texas Southern (2-9) | 26 | at SWAC | ||
| 9/8/2018 | Texas-Permian Basin | 22 | at | Northern Michigan (3-8) | 27 | at GLIAC | ||
| 9/15/2018 | Midwestern State (8-2,6-2) | 43 | at | Texas-Permian Basin | 21 | |||
| 9/22/2018 | Texas-Permian Basin | 13 | at | Tarleton State (12-1,9-0) | 35 | |||
| 9/29/2018 | Western New Mexico (0-10,0-8) | 20 | at | Texas-Permian Basin | 21 | |||
| 10/6/2018 | Texas-Permian Basin | 21 | at | West Texas A&M (6-5,4-4) | 42 | |||
| 10/13/2018 | Humboldt State (2-8) | 17 | at | Texas-Permian Basin | 36 | GNWAC | ||
| 10/20/2018 | Angelo State (6-6,4-4) | 44 | at | Texas-Permian Basin | 20 | |||
| 10/27/2018 | Texas-Permian Basin | 7 | at | Eastern New Mexico (5-6,4-4) | 24 | |||
| 11/3/2018 | Texas A&M-Commerce (10-3,7-2) | 20 | at | Texas-Permian Basin | 17 | |||
| 11/10/2018 | Texas-Permian Basin | 21 | at | Texas A&M-Kingsville (4-7,2-6) | 24 |
| vs Texas-Permian Basin | vs Other Opponents | Texas-Permian Basin compared to OOs | |
| Record: | 9-2 | 49-63 | |
| Points Scored: | 29.27 | 27.96 | -1.31 |
| Points Allowed: | 19.55 | 29.03 | -9.48 |
| Margin: | 9.72 | -1.07 | -10.79 |
| Total Points: | 48.82 | 56.99 | -8.17 |