| 8/30/2018 | Delta State (2-8) | 13 | at | Tarleton State | 44 | GSC | ||
| 9/8/2018 | Tarleton State | at | Stephen F. Austin (2-8) | CCD | at SLC | |||
| 9/15/2018 | Tarleton State | 44 | at | West Texas A&M (6-5,4-4) | 7 | |||
| 9/22/2018 | Texas-Permian Basin (2-9,1-7) | 13 | at | Tarleton State | 35 | |||
| 9/29/2018 | Tarleton State | 54 | at | Angelo State (6-6,4-4) | 33 | |||
| 10/6/2018 | Eastern New Mexico (5-6,4-4) | 28 | at | Tarleton State | 48 | |||
| 10/13/2018 | Tarleton State | 47 | at | Texas A&M-Commerce (10-3,7-2) | 21 | |||
| 10/20/2018 | Texas A&M-Kingsville (4-7,2-6) | 21 | at | Tarleton State | 59 | |||
| 10/27/2018 | Tarleton State | 35 | at | Midwestern State (8-2,6-2) | 34 | OT | ||
| 11/3/2018 | Lincoln MO (3-8) | 3 | at | Tarleton State | 59 | GLV | ||
| 11/10/2018 | Western New Mexico (0-10,0-8) | 0 | at | Tarleton State | 58 | |||
| 11/17/2018 | Azusa Pacific (8-4) | 0 | at | Tarleton State | 58 | D2 Playoff Round 1 | GNWAC | |
| 11/24/2018 | Texas A&M-Commerce (10-3,7-2) | 28 | at | Tarleton State | 34 | |||
| 12/1/2018 | Tarleton State | 10 | at | Minnesota State-Mankato (13-1) | 13 | D2 Playoff | at NSIC |
| vs Tarleton State | vs Other Opponents | Tarleton State compared to OOs | |
| Record: | 1-12 | 78-66 | |
| Points Scored: | 16.46 | 28.26 | 11.80 |
| Points Allowed: | 45.00 | 25.72 | 19.28 |
| Margin: | -28.54 | 2.54 | 31.08 |
| Total Points: | 61.46 | 53.98 | 7.48 |