| 8/30/2018 | Southwest Minnesota State (4-7,4-7) | 13 | at | Minnesota State-Mankato | 49 | | | |
| 9/8/2018 | Minnesota State-Mankato | 38 | at | Augustana SD (7-4,7-4) | 36 | | | |
| 9/15/2018 | Concordia-St Paul (5-6,5-6) | 13 | at | Minnesota State-Mankato | 46 | | | |
| 9/22/2018 | Minnesota State-Mankato | 31 | at | Winona State (8-3,8-3) | 21 | | | |
| 9/29/2018 | Saint Cloud State (7-4,7-4) | 10 | at | Minnesota State-Mankato | 45 | | | |
| 10/6/2018 | Minnesota State-Mankato | 42 | at | Minnesota State-Moorhead (8-4,8-3) | 20 | | | |
| 10/13/2018 | Minot State (1-10,1-10) | 13 | at | Minnesota State-Mankato | 62 | | | |
| 10/20/2018 | Minnesota State-Mankato | 47 | at | Bemidji State (7-4,7-4) | 20 | | | |
| 10/27/2018 | Minnesota State-Mankato | 55 | at | Wayne State NE (3-8,3-8) | 2 | | | |
| 11/3/2018 | Sioux Falls (7-4,7-4) | 21 | at | Minnesota State-Mankato | 31 | | | |
| 11/10/2018 | Upper Iowa (3-8,3-8) | 7 | at | Minnesota State-Mankato | 47 | | | |
| 11/24/2018 | Colorado State-Pueblo (11-2) | 10 | at | Minnesota State-Mankato | 24 | | | RMAC |
| 12/1/2018 | Tarleton State (12-1) | 10 | at | Minnesota State-Mankato | 13 | | D2 Playoff | LSC |
| 12/8/2018 | Ferris State (15-1) | 42 | at | Minnesota State-Mankato | 25 | | D2 Playoff Seminfinal | GLIAC |