| 8/30/2018 | Eastern New Mexico (5-6) | 14 | at | Missouri S&T | 31 | LSC | ||
| 9/8/2018 | Missouri S&T | 27 | at | Northwood (3-7) | 16 | at GLIAC | ||
| 9/15/2018 | Missouri S&T | 12 | at | Drake (7-4) | 52 | at Pio | ||
| 9/22/2018 | Missouri S&T | 16 | at | Tuskegee (5-5) | 7 | at SIAC | ||
| 9/29/2018 | Missouri S&T | 48 | at | Southwest Baptist (0-10,0-7) | 23 | |||
| 10/6/2018 | Indianapolis (10-2,7-0) | 24 | at | Missouri S&T | 17 | |||
| 10/13/2018 | William Jewell (1-9,1-6) | 21 | at | Missouri S&T | 59 | |||
| 10/20/2018 | Missouri S&T | 20 | at | Quincy (4-7,3-4) | 13 | |||
| 10/27/2018 | Lincoln MO (3-8,2-5) | 7 | at | Missouri S&T | 45 | |||
| 11/3/2018 | Missouri S&T | 49 | at | McKendree (6-5,4-3) | 20 | |||
| 11/10/2018 | Truman State (6-5,5-2) | 33 | at | Missouri S&T | 34 | |||
| 12/1/2018 | Minnesota State-Moorhead (8-4) | 16 | vs | Missouri S&T | 51 | Excelsior Springs MO | NSIC |
| vs Missouri S&T | vs Other Opponents | Missouri S&T compared to OOs | |
| Record: | 2-10 | 56-62 | |
| Points Scored: | 20.50 | 24.05 | 3.55 |
| Points Allowed: | 34.08 | 27.16 | 6.92 |
| Margin: | -13.58 | -3.11 | 10.47 |
| Total Points: | 54.58 | 51.21 | 3.37 |