| 9/3/2016 | Augustana IL (3-7) | 21 | at | Mt St Joseph | 10 | CCIW | ||
| 9/10/2016 | Mt St Joseph | 13 | at | DePauw (8-2) | 44 | at NCA | ||
| 9/17/2016 | Mt St Joseph | 6 | at | Bluffton (7-3,5-3) | 16 | |||
| 9/24/2016 | Manchester (2-8,2-6) | 19 | at | Mt St Joseph | 38 | |||
| 10/1/2016 | Mt St Joseph | 42 | at | Hanover (4-6,4-4) | 6 | |||
| 10/8/2016 | Rose-Hulman (8-3,7-1) | 27 | at | Mt St Joseph | 45 | |||
| 10/15/2016 | Mt St Joseph | 61 | at | Earlham (0-10,0-8) | 7 | |||
| 10/22/2016 | Anderson (1-9,1-7) | 7 | at | Mt St Joseph | 51 | |||
| 10/29/2016 | Franklin (8-2,7-1) | 56 | at | Mt St Joseph | 24 | |||
| 11/5/2016 | Mt St Joseph | 21 | at | Defiance (5-5,4-4) | 20 |
| vs Mt St Joseph | vs Other Opponents | Mt St Joseph compared to OOs | |
| Record: | 4-6 | 42-49 | |
| Points Scored: | 22.30 | 27.05 | 4.75 |
| Points Allowed: | 31.10 | 29.40 | 1.70 |
| Margin: | -8.80 | -2.35 | 6.45 |
| Total Points: | 53.40 | 56.45 | -3.05 |