| 9/3/2016 | Wilmington (0-10) | 20 | at | Bluffton | 49 | OAC | ||
| 9/10/2016 | Bluffton | 37 | at | Trine (6-4) | 31 | at MIAA | ||
| 9/17/2016 | Mt St Joseph (6-4,6-2) | 6 | at | Bluffton | 16 | |||
| 9/24/2016 | Bluffton | 38 | at | Franklin (8-2,7-1) | 44 | |||
| 10/8/2016 | Bluffton | 62 | at | Anderson (1-9,1-7) | 22 | |||
| 10/15/2016 | Hanover (4-6,4-4) | 18 | at | Bluffton | 28 | |||
| 10/22/2016 | Manchester (2-8,2-6) | 6 | at | Bluffton | 34 | |||
| 10/29/2016 | Bluffton | 19 | at | Rose-Hulman (8-3,7-1) | 42 | |||
| 11/5/2016 | Bluffton | 54 | at | Earlham (0-10,0-8) | 20 | |||
| 11/12/2016 | Defiance (5-5,4-4) | 28 | at | Bluffton | 20 |
| vs Bluffton | vs Other Opponents | Bluffton compared to OOs | |
| Record: | 3-7 | 37-54 | |
| Points Scored: | 23.70 | 24.88 | 1.18 |
| Points Allowed: | 35.70 | 31.90 | 3.80 |
| Margin: | -12.00 | -7.02 | 4.98 |
| Total Points: | 59.40 | 56.78 | 2.62 |