| 9/3/2016 | Illinois College (6-4) | 14 | at | Rose-Hulman | 13 | MidW | ||
| 9/10/2016 | Rose-Hulman | 26 | at | Millikin (4-6) | 14 | at CCIW | ||
| 9/17/2016 | Rose-Hulman | 31 | at | Hanover (4-6,4-4) | 13 | |||
| 9/24/2016 | Rose-Hulman | 23 | at | Defiance (5-5,4-4) | 15 | |||
| 10/1/2016 | Anderson (1-9,1-7) | 10 | at | Rose-Hulman | 44 | |||
| 10/8/2016 | Rose-Hulman | 27 | at | Mt St Joseph (6-4,6-2) | 45 | |||
| 10/15/2016 | Manchester (2-8,2-6) | 9 | at | Rose-Hulman | 44 | |||
| 10/22/2016 | Rose-Hulman | 23 | at | Franklin (8-2,7-1) | 22 | |||
| 10/29/2016 | Bluffton (7-3,5-3) | 19 | at | Rose-Hulman | 42 | |||
| 11/12/2016 | Earlham (0-10,0-8) | 6 | at | Rose-Hulman | 74 | |||
| 11/19/2016 | Rose-Hulman | 7 | at | North Central (11-1) | 41 | at CCIW |
| vs Rose-Hulman | vs Other Opponents | Rose-Hulman compared to OOs | |
| Record: | 3-8 | 51-50 | |
| Points Scored: | 18.91 | 28.01 | 9.10 |
| Points Allowed: | 32.18 | 29.36 | 2.82 |
| Margin: | -13.27 | -1.35 | 11.92 |
| Total Points: | 51.09 | 57.37 | -6.28 |