| 9/1/2016 | Trine (6-4) | 23 | at | Manchester | 9 | MIAA | ||
| 9/10/2016 | Alma (7-3) | 31 | at | Manchester | 20 | MIAA | ||
| 9/24/2016 | Manchester | 19 | at | Mt St Joseph (6-4,6-2) | 38 | |||
| 10/1/2016 | Franklin (8-2,7-1) | 41 | at | Manchester | 27 | |||
| 10/8/2016 | Defiance (5-5,4-4) | 20 | at | Manchester | 14 | |||
| 10/15/2016 | Manchester | 9 | at | Rose-Hulman (8-3,7-1) | 44 | |||
| 10/22/2016 | Manchester | 6 | at | Bluffton (7-3,5-3) | 34 | |||
| 10/29/2016 | Earlham (0-10,0-8) | 13 | at | Manchester | 65 | |||
| 11/5/2016 | Hanover (4-6,4-4) | 49 | at | Manchester | 27 | |||
| 11/12/2016 | Manchester | 33 | at | Anderson (1-9,1-7) | 14 |
| vs Manchester | vs Other Opponents | Manchester compared to OOs | |
| Record: | 8-2 | 44-47 | |
| Points Scored: | 30.70 | 28.03 | -2.67 |
| Points Allowed: | 22.90 | 29.64 | -6.74 |
| Margin: | 7.80 | -1.61 | -9.41 |
| Total Points: | 53.60 | 57.67 | -4.07 |