| 9/3/2016 | Wilmington | 20 | at | Bluffton (7-3) | 49 | at HCA | ||
| 9/17/2016 | Otterbein (5-5,5-4) | 52 | at | Wilmington | 7 | |||
| 9/24/2016 | Wilmington | 21 | at | Capital (4-6,4-5) | 35 | |||
| 10/1/2016 | John Carroll (12-2,9-0) | 67 | at | Wilmington | 7 | |||
| 10/8/2016 | Baldwin-Wallace (3-7,2-7) | 28 | at | Wilmington | 17 | |||
| 10/15/2016 | Wilmington | 23 | at | Marietta (3-7,3-6) | 66 | |||
| 10/22/2016 | Wilmington | 7 | at | Mount Union (12-2,8-1) | 71 | |||
| 10/29/2016 | Heidelberg (6-4,6-3) | 59 | at | Wilmington | 3 | |||
| 11/5/2016 | Wilmington | 3 | at | Ohio Northern (5-5,5-4) | 80 | |||
| 11/12/2016 | Muskingum (4-6,3-6) | 37 | at | Wilmington | 7 |
| vs Wilmington | vs Other Opponents | Wilmington compared to OOs | |
| Record: | 10-0 | 51-47 | |
| Points Scored: | 54.40 | 29.02 | -25.38 |
| Points Allowed: | 11.50 | 27.19 | -15.69 |
| Margin: | 42.90 | 1.83 | -41.07 |
| Total Points: | 65.90 | 56.21 | 9.69 |