| 9/2/2016 | Northwestern State | 7 | at | Baylor (7-6) | 55 | at B12 | ||
| 9/8/2016 | Incarnate Word (3-8,3-6) | 21 | at | Northwestern State | 18 | |||
| 9/17/2016 | Northwestern State | 10 | at | Central Arkansas (10-3,8-1) | 24 | |||
| 9/24/2016 | Northwestern State | 24 | at | Southeastern Louisiana (7-4,7-2) | 34 | |||
| 10/8/2016 | Kentucky Wesleyan (3-8) | 7 | at | Northwestern State | 49 | D2Ind (D2) | ||
| 10/15/2016 | Northwestern State | 31 | at | Lamar (3-8,3-6) | 32 | |||
| 10/22/2016 | McNeese State (6-5,5-4) | 48 | at | Northwestern State | 27 | |||
| 10/29/2016 | Nicholls State (5-6,5-4) | 31 | at | Northwestern State | 14 | |||
| 11/5/2016 | Northwestern State | 22 | at | Abilene Christian (2-9,2-7) | 25 | |||
| 11/12/2016 | Sam Houston (12-1,9-0) | 48 | at | Northwestern State | 16 | |||
| 11/19/2016 | Northwestern State | 31 | at | Stephen F. Austin (5-6,4-5) | 45 |
| vs Northwestern State | vs Other Opponents | Northwestern State compared to OOs | |
| Record: | 10-1 | 53-63 | |
| Points Scored: | 33.64 | 30.63 | -3.01 |
| Points Allowed: | 22.64 | 32.13 | -9.49 |
| Margin: | 11.00 | -1.50 | -12.50 |
| Total Points: | 56.28 | 62.76 | -6.48 |