| 9/3/2016 | Butler (4-7) | 25 | at | Indiana State | 41 | Pio | ||
| 9/10/2016 | Indiana State | 28 | at | Minnesota (9-4) | 58 | at B10 | ||
| 9/17/2016 | Indiana State | 27 | at | SE Missouri State (3-8) | 24 | at OVC | ||
| 9/24/2016 | Illinois State (6-6,4-4) | 31 | at | Indiana State | 34 | |||
| 10/1/2016 | Missouri State (4-7,2-6) | 45 | at | Indiana State | 24 | |||
| 10/8/2016 | Indiana State | 35 | at | Western Illinois (6-5,3-5) | 36 | |||
| 10/15/2016 | South Dakota (4-7,3-5) | 33 | at | Indiana State | 30 | 2OT | ||
| 10/22/2016 | Indiana State | 22 | at | Southern Illinois (4-7,2-6) | 14 | |||
| 10/29/2016 | Indiana State | 10 | at | Youngstown State (12-4,6-2) | 13 | |||
| 11/5/2016 | Northern Iowa (5-6,4-4) | 39 | at | Indiana State | 6 | |||
| 11/12/2016 | Indiana State | 17 | at | North Dakota State (12-2,8-1) | 41 |
| vs Indiana State | vs Other Opponents | Indiana State compared to OOs | |
| Record: | 7-4 | 62-59 | |
| Points Scored: | 32.64 | 26.84 | -5.80 |
| Points Allowed: | 24.91 | 25.70 | -0.79 |
| Margin: | 7.73 | 1.14 | -6.59 |
| Total Points: | 57.55 | 52.54 | 5.01 |