| 9/2/2010 | Valparaiso | @ | Western Illinois | ||||||
| 9/11/2010 | Western Illinois | @ | Purdue | ||||||
| 9/18/2010 | Sam Houston | @ | Western Illinois | ||||||
| 9/25/2010 | Indiana St | @ | Western Illinois | MVC | |||||
| 10/2/2010 | Western Illinois | @ | N Dakota St | MVC | |||||
| 10/9/2010 | Western Illinois | @ | S Dakota St | MVC | |||||
| 10/16/2010 | Youngstown St | @ | Western Illinois | MVC | |||||
| 10/23/2010 | Western Illinois | @ | Missouri State | MVC | |||||
| 10/30/2010 | Illinois St | @ | Western Illinois | MVC | |||||
| 11/13/2010 | Western Illinois | @ | Southern Illinois | MVC | |||||
| 11/20/2010 | Northern Iowa | @ | Western Illinois | MVC |