| 9/4/2010 | Youngstown St | @ | Penn State | ||||||
| 9/11/2010 | Butler | @ | Youngstown St | ||||||
| 9/18/2010 | Central Conn | @ | Youngstown St | ||||||
| 9/25/2010 | Southern Illinois | @ | Youngstown St | MVC | |||||
| 10/2/2010 | Youngstown St | @ | Missouri State | MVC | |||||
| 10/9/2010 | N Dakota St | @ | Youngstown St | MVC | |||||
| 10/16/2010 | Youngstown St | @ | Western Illinois | MVC | |||||
| 10/23/2010 | Youngstown St | @ | S Dakota St | MVC | |||||
| 10/30/2010 | Northern Iowa | @ | Youngstown St | MVC | |||||
| 11/6/2010 | Youngstown St | @ | Illinois St | MVC | |||||
| 11/13/2010 | Indiana St | @ | Youngstown St | MVC |