| 8/30/2008 | Tennessee St | 34 | @ | Alabama A&M | 13 | ||||
| 9/6/2008 | Southern Univ | 32 | @ | Tennessee St | 34 | ||||
| 9/13/2008 | Jackson St | 18 | vs | Tennessee St | 41 | ||||
| 9/20/2008 | Eastern Kentucky | 20 | @ | Tennessee St | 34 | OVC | |||
| 9/27/2008 | Florida A&M | 28 | vs | Tennessee St | 21 | ||||
| 10/4/2008 | Tennessee St | 30 | @ | Tennessee-Martin | 27 | OT | OVC | ||
| 10/18/2008 | Austin Peay | 34 | @ | Tennessee St | 37 | OVC | |||
| 10/25/2008 | Tennessee St | 20 | @ | SE Missouri St | 27 | OVC | |||
| 11/1/2008 | Tennessee Tech | 14 | @ | Tennessee St | 41 | OVC | |||
| 11/8/2008 | Eastern Illinois | 24 | @ | Tennessee St | 45 | OVC | |||
| 11/15/2008 | Tennessee St | 21 | @ | Jacksonville St | 26 | OVC | |||
| 11/22/2008 | Tennessee St | 17 | @ | Murray St | 24 | OVC |