| 8/28/2008 | Jacksonville St | 14 | @ | Georgia Tech | 41 | ||||
| 9/6/2008 | Alabama A&M | 18 | @ | Jacksonville St | 45 | ||||
| 9/20/2008 | Jacksonville St | 31 | @ | Chattanooga | 3 | ||||
| 9/27/2008 | Jacksonville St | 23 | @ | Eastern Illinois | 10 | OT | OVC | ||
| 10/4/2008 | SE Missouri St | 17 | @ | Jacksonville St | 38 | OVC | |||
| 10/11/2008 | Jacksonville St | 35 | @ | Eastern Kentucky | 38 | OVC | |||
| 10/18/2008 | Murray St | 21 | @ | Jacksonville St | 31 | OVC | |||
| 10/23/2008 | Jacksonville St | 30 | @ | Tennessee-Martin | 31 | OVC | |||
| 11/1/2008 | Austin Peay | 22 | @ | Jacksonville St | 35 | OVC | |||
| 11/8/2008 | Jacksonville St | 41 | @ | Tennessee Tech | 17 | OVC | |||
| 11/15/2008 | Tennessee St | 21 | @ | Jacksonville St | 26 | OVC |