| 9/3/2005 | Maine | 7 | @ | Nebraska | 25 | ||||
| 9/10/2005 | Wake Forest | 3 | @ | Nebraska | 31 | ||||
| 9/17/2005 | Pittsburgh | 6 | @ | Nebraska | 7 | ||||
| 10/1/2005 | Iowa State | 20 | @ | Nebraska | 27 | 2 OT | B12 | ||
| 10/8/2005 | #15 Texas Tech | 34 | @ | Nebraska | 31 | B12 | |||
| 10/15/2005 | Nebraska | 23 | @ | Baylor | 14 | B12 | |||
| 10/22/2005 | Nebraska | 24 | @ | Missouri | 41 | B12 | |||
| 10/29/2005 | Oklahoma | 31 | @ | Nebraska | 24 | B12 | |||
| 11/5/2005 | Nebraska | 15 | @ | Kansas | 40 | B12 | |||
| 11/12/2005 | Kansas St | 25 | @ | Nebraska | 27 | B12 | |||
| 11/25/2005 | Nebraska | 30 | @ | Colorado | 3 | B12 | |||
| 12/28/2005 | #20 Michigan | 28 | vs | Nebraska | 32 | Alamo |