| 9/3/2005 | Colorado St | 28 | @ | Colorado | 31 | ||||
| 9/10/2005 | New Mexico St | 0 | @ | Colorado | 39 | ||||
| 9/24/2005 | Colorado | 3 | @ | #9 Miami-Florida | 23 | ||||
| 10/1/2005 | Colorado | 34 | @ | Oklahoma St | 0 | B12 | |||
| 10/8/2005 | Texas A&M | 20 | @ | Colorado | 41 | B12 | |||
| 10/15/2005 | Colorado | 17 | @ | #2 Texas | 42 | B12 | |||
| 10/22/2005 | Kansas | 13 | @ | Colorado | 44 | B12 | |||
| 10/29/2005 | Colorado | 23 | @ | Kansas St | 20 | B12 | |||
| 11/5/2005 | Missouri | 12 | @ | Colorado | 41 | B12 | |||
| 11/12/2005 | Colorado | 16 | @ | Iowa State | 30 | B12 | |||
| 11/25/2005 | Nebraska | 30 | @ | Colorado | 3 | B12 | |||
| 12/3/2005 | #2 Texas | 70 | vs | Colorado | 3 | B12 | B12 CG | ||
| 12/27/2005 | #23 Clemson | 19 | vs | Colorado | 10 | Champs Sports |