| 9/11/2010 | Whitworth Pirates 35 @ Pomona-Pitzer 7 | |
| 9/18/2010 | Pomona-Pitzer 38 @ Lewis & Clark Pioneers 63 | |
| 10/2/2010 | Pomona-Pitzer 17 @ Chapman Panthers 41 | |
| 10/9/2010 | Redlands Bulldogs 38 @ Pomona-Pitzer 26 | † |
| 10/16/2010 | Pomona-Pitzer 26 @ Occidental Tigers 39 | † |
| 10/23/2010 | Pomona-Pitzer 7 @ Cal Lutheran Kingsmen 38 | † |
| 10/30/2010 | Whittier Poets 37 @ Pomona-Pitzer 17 | † |
| 11/6/2010 | Pomona-Pitzer 28 @ La Verne Leopards 26 3OT | † |
| 11/13/2010 | Claremont-Mudd-Scripps Staggs 31 @ Pomona-Pitzer 30 | † |