| 9/11/2010 | Chapman 10 @ Menlo Oaks 21 |
| 9/25/2010 | Azusa Pacific Cougars 35 @ Chapman 17 |
| 10/2/2010 | Pomona-Pitzer Sagehens 17 @ Chapman 41 |
| 10/9/2010 | Chapman 21 @ Claremont-Mudd-Scripps Staggs 31 |
| 10/16/2010 | Chapman 29 @ Whittier Poets 17 |
| 10/23/2010 | La Verne Leopards 28 @ Chapman 35 |
| 10/30/2010 | Occidental Tigers 24 @ Chapman 28 |
| 11/6/2010 | Chapman 6 @ Cal Lutheran Kingsmen 27 |
| 11/13/2010 | Chapman 17 @ Redlands Bulldogs 21 |