| 9/11/2010 | Capital 7 @ Baldwin-Wallace Yellow Jackets 10 | † |
| 9/18/2010 | Capital 10 @ Wilmington Quakers 7 | † |
| 9/25/2010 | Wesley Wolverines 42 @ Capital 21 | |
| 10/2/2010 | Heidelberg Fighting Student Princes 50 @ Capital 60 | † |
| 10/9/2010 | Capital 10 @ Ohio Northern Polar Bears 44 | † |
| 10/16/2010 | Otterbein Cardinals 13 @ Capital 23 | † |
| 10/23/2010 | Capital 0 @ Mount Union Purple Raiders 38 | † |
| 10/30/2010 | John Carroll Blue Streaks 28 @ Capital 20 | † |
| 11/6/2010 | Capital 27 @ Muskingum Muskies 24 | † |
| 11/13/2010 | Marietta Pioneers 31 @ Capital 34 | † |