| 9/3/2010 | Otterbein Cardinals 38 @ Husson 0 | |
| 9/11/2010 | Springfield Pride 51 @ Husson 0 | |
| 9/18/2010 | Salisbury Seagulls 84 @ Husson 7 | |
| 9/25/2010 | Husson 21 @ SUNY-Maritime Privateers 47 | † |
| 10/2/2010 | Gallaudet Bison 13 @ Husson 6 | † |
| 10/9/2010 | Husson 53 @ Anna Maria Amcats 38 | † |
| 10/16/2010 | Husson 7 @ Norwich Cadets 52 | † |
| 10/23/2010 | Castleton State Spartans 55 @ Husson 51 | † |
| 10/30/2010 | Mount Ida Mustangs 25 @ Husson 23 | † |
| 11/6/2010 | Husson 23 @ Becker Hawks 27 | † |