| 8/28/2010 | Wingate Bulldogs 10 @ West Georgia 7 | |
| 9/4/2010 | Concordia AL Hornets 20 @ West Georgia 24 | |
| 9/16/2010 | Harding Bison 21 @ West Georgia 28 | † |
| 9/23/2010 | West Georgia 7 @ West Alabama Tigers 28 | † |
| 10/2/2010 | Southern Arkansas Muleriders 17 @ West Georgia 31 | † |
| 10/9/2010 | North Alabama Lions 17 @ West Georgia 10 | † |
| 10/16/2010 | West Georgia 24 @ Arkansas-Monticello Boll Weevils 31 | † |
| 10/23/2010 | Delta State Statesmen 54 @ West Georgia 34 | † |
| 11/6/2010 | West Georgia 19 @ Valdosta State Blazers 31 | † |
| 11/13/2010 | West Georgia 6 @ Henderson State Reddies 40 | † |