| 9/12/2009 | Ga Southern 6 @ S Dakota St 44 | |
| 9/19/2009 | Indiana St 0 @ S Dakota St 41 | † |
| 9/26/2009 | S Dakota St 38 @ Illinois St 17 | † |
| 10/3/2009 | S Dakota St 14 @ Cal Poly 21 | |
| 10/10/2009 | S Dakota St 24 @ Missouri State 17 | † |
| 10/17/2009 | N Dakota St 13 @ S Dakota St 28 | † |
| 10/24/2009 | Northern Iowa 14 @ S Dakota St 24 | † |
| 10/31/2009 | S Dakota St 17 @ Youngstown St 3 | † |
| 11/7/2009 | Southern Illinois 34 @ S Dakota St 15 | † |
| 11/14/2009 | S Dakota St 13 @ Minnesota 16 | |
| 11/21/2009 | S Dakota St 27 @ Western Illinois 7 | † |
| 11/28/2009 | S Dakota St 48 @ Montana 61 (FCS Playoff round 1) |