| 8/29/2024 | Eastern Illinois | 0 | at | Illinois | 45 | BigS (1AA) | ||
| North Carolina | 19 | at | Minnesota | 17 | ACC | |||
| Howard | 7 | at | Rutgers | 44 | MEAC (1AA) | |||
| 8/30/2024 | Florida Atlantic | 10 | at | Michigan State | 16 | AAC | ||
| Western Michigan | 14 | at | Wisconsin | 28 | MAC | |||
| 8/31/2024 | UCLA | 16 | at | Hawaii | 13 | @ MW | ||
| Florida Intl | 7 | at | Indiana | 31 | CUSA | |||
| Illinois State | 0 | at | Iowa | 40 | MVC (1AA) | |||
| Connecticut | 7 | at | Maryland | 50 | Ind | |||
| Fresno State | 10 | at | Michigan | 30 | MW | |||
| UTEP | 7 | at | Nebraska | 40 | CUSA | |||
| Miami-Ohio | 6 | at | Northwestern | 13 | MAC | |||
| Akron | 6 | at | Ohio State | 52 | MAC | |||
| Idaho | 14 | at | Oregon | 24 | BSky (1AA) | |||
| Indiana State | 0 | at | Purdue | 49 | MVC (1AA) | |||
| Weber State | 3 | at | Washington | 35 | BSky (1AA) | |||
| Penn State | 34 | at | West Virginia | 12 | @ B12 | |||
| 9/1/2024 | LSU | 20 | vs | Southern California | 27 | Las Vegas NV | vs SEC | |
| 9/6/2024 | Western Illinois | 3 | at | Indiana | 77 | BigS (1AA) | ||
| Duke | 26 | at | Northwestern | 20 | ACC | |||
| 9/7/2024 | Kansas | 17 | at | Illinois | 23 | B12 | ||
| Iowa State | 20 | at | Iowa | 19 | B12 | |||
| Michigan State | 27 | at | Maryland | 24 | ||||
| Texas | 31 | at | Michigan | 12 | SEC | |||
| Rhode Island | 0 | at | Minnesota | 48 | CAAF (1AA) | |||
| Colorado | 10 | at | Nebraska | 28 | B12 | |||
| Western Michigan | 0 | at | Ohio State | 56 | MAC | |||
| Boise State | 34 | at | Oregon | 37 | MW | |||
| Bowling Green | 27 | at | Penn State | 34 | MAC | |||
| Akron | 17 | at | Rutgers | 49 | MAC | |||
| Utah State | 0 | at | Southern California | 48 | MW | |||
| Eastern Michigan | 9 | at | Washington | 30 | MAC | |||
| South Dakota | 13 | at | Wisconsin | 27 | MVC (1AA) | |||
| 9/14/2024 | Central Michigan | 9 | at | Illinois | 30 | MAC | ||
| Troy | 21 | at | Iowa | 38 | SBC | |||
| Arkansas State | 18 | at | Michigan | 28 | SBC | |||
| Prairie View | 0 | at | Michigan State | 40 | SWAC (1AA) | |||
| Nevada | 0 | at | Minnesota | 27 | MW | |||
| Northern Iowa | 3 | at | Nebraska | 34 | MVC (1AA) | |||
| Eastern Illinois | 7 | at | Northwestern | 31 | BigS (1AA) | |||
| Oregon | 49 | at | Oregon State | 14 | @ P12 | |||
| Notre Dame | 66 | at | Purdue | 7 | ND | |||
| Indiana | 42 | at | UCLA | 13 | ||||
| Maryland | 27 | at | Virginia | 13 | @ ACC | |||
| Washington State | 24 | at | Washington | 19 | P12 | |||
| Alabama | 42 | at | Wisconsin | 10 | SEC | |||
| 9/20/2024 | Illinois | 31 | at | Nebraska | 24 | |||
| 9/21/2024 | Michigan State | 19 | at | Boston College | 23 | @ ACC | ||
| UNC-Charlotte | 14 | at | Indiana | 52 | AAC | |||
| UCLA | 17 | at | LSU | 34 | @ SEC | |||
| Villanova | 20 | at | Maryland | 38 | CAAF (1AA) | |||
| Southern California | 24 | at | Michigan | 27 | ||||
| Iowa | 31 | at | Minnesota | 14 | ||||
| Marshall | 14 | at | Ohio State | 49 | SBC | |||
| Purdue | 21 | at | Oregon State | 38 | @ P12 | |||
| Kent State | 0 | at | Penn State | 56 | MAC | |||
| Rutgers | 26 | at | Virginia Tech | 23 | @ ACC | |||
| Northwestern | 5 | at | Washington | 24 | ||||
| 9/27/2024 | Washington | 18 | at | Rutgers | 21 | |||
| 9/28/2024 | Maryland | 28 | at | Indiana | 42 | |||
| Minnesota | 24 | at | Michigan | 27 | ||||
| Ohio State | 38 | at | Michigan State | 7 | ||||
| Illinois | 7 | at | Penn State | 21 | ||||
| Nebraska | 28 | at | Purdue | 10 | ||||
| Wisconsin | 21 | at | Southern California | 38 | ||||
| Oregon | 34 | at | UCLA | 13 | ||||
| 10/4/2024 | Michigan State | 10 | at | Oregon | 31 | |||
| 10/5/2024 | Southern California | 17 | at | Minnesota | 24 | |||
| Rutgers | 7 | at | Nebraska | 14 | ||||
| Indiana | 41 | at | Northwestern | 24 | ||||
| Iowa | 7 | at | Ohio State | 35 | ||||
| UCLA | 11 | at | Penn State | 27 | ||||
| Michigan | 17 | at | Washington | 27 | ||||
| Purdue | 6 | at | Wisconsin | 52 | ||||
| 10/11/2024 | Northwestern | 37 | at | Maryland | 10 | |||
| 10/12/2024 | Purdue | 49 | at | Illinois | 50 | |||
| Washington | 16 | at | Iowa | 40 | ||||
| Ohio State | 31 | at | Oregon | 32 | ||||
| Wisconsin | 42 | at | Rutgers | 7 | ||||
| Penn State | 33 | at | Southern California | 30 | ||||
| Minnesota | 21 | at | UCLA | 17 | ||||
| 10/18/2024 | Oregon | 35 | at | Purdue | 0 | |||
| 10/19/2024 | Michigan | 7 | at | Illinois | 21 | |||
| Nebraska | 7 | at | Indiana | 56 | ||||
| Southern California | 28 | at | Maryland | 29 | ||||
| Iowa | 20 | at | Michigan State | 32 | ||||
| Wisconsin | 23 | at | Northwestern | 3 | ||||
| UCLA | 35 | at | Rutgers | 32 | ||||
| 10/25/2024 | Rutgers | 20 | at | Southern California | 42 | |||
| 10/26/2024 | Washington | 17 | at | Indiana | 31 | |||
| Northwestern | 14 | at | Iowa | 40 | ||||
| Michigan State | 17 | at | Michigan | 24 | ||||
| Maryland | 23 | at | Minnesota | 48 | ||||
| Nebraska | 17 | at | Ohio State | 21 | ||||
| Illinois | 9 | at | Oregon | 38 | ||||
| Penn State | 28 | at | Wisconsin | 13 | ||||
| 11/2/2024 | Minnesota | 25 | at | Illinois | 17 | |||
| Wisconsin | 10 | at | Iowa | 42 | ||||
| Oregon | 38 | at | Michigan | 17 | ||||
| Indiana | 47 | at | Michigan State | 10 | ||||
| UCLA | 27 | at | Nebraska | 20 | ||||
| Ohio State | 20 | at | Penn State | 13 | ||||
| Northwestern | 26 | at | Purdue | 20 | OT | |||
| Southern California | 21 | at | Washington | 26 | ||||
| 11/8/2024 | Iowa | 17 | at | UCLA | 20 | |||
| 11/9/2024 | Michigan | 15 | at | Indiana | 20 | |||
| Purdue | 0 | at | Ohio State | 45 | ||||
| Maryland | 18 | at | Oregon | 39 | ||||
| Washington | 6 | at | Penn State | 35 | ||||
| Minnesota | 19 | at | Rutgers | 26 | ||||
| 11/15/2024 | UCLA | 19 | at | Washington | 31 | |||
| 11/16/2024 | Michigan State | 16 | at | Illinois | 38 | |||
| Rutgers | 31 | at | Maryland | 17 | ||||
| Ohio State | 31 | vs | Northwestern | 7 | Chicago IL | |||
| Penn State | 49 | at | Purdue | 10 | ||||
| Nebraska | 20 | at | Southern California | 28 | ||||
| Oregon | 16 | at | Wisconsin | 13 | ||||
| 11/22/2024 | Purdue | 17 | at | Michigan State | 24 | |||
| 11/23/2024 | Iowa | 29 | at | Maryland | 13 | |||
| Northwestern | 6 | at | Michigan | 50 | ||||
| Penn State | 26 | at | Minnesota | 25 | ||||
| Wisconsin | 25 | at | Nebraska | 44 | ||||
| Indiana | 15 | at | Ohio State | 38 | ||||
| Illinois | 38 | at | Rutgers | 31 | ||||
| Southern California | 19 | at | UCLA | 13 | ||||
| 11/29/2024 | Nebraska | 10 | at | Iowa | 13 | |||
| Minnesota | 24 | at | Wisconsin | 7 | ||||
| 11/30/2024 | Purdue | 0 | at | Indiana | 66 | |||
| Rutgers | 41 | at | Michigan State | 14 | ||||
| Illinois | 38 | vs | Northwestern | 28 | Chicago IL | |||
| Michigan | 13 | at | Ohio State | 10 | ||||
| Washington | 21 | at | Oregon | 49 | ||||
| Maryland | 7 | at | Penn State | 44 | ||||
| Notre Dame | 49 | at | Southern California | 35 | ND | |||
| Fresno State | 13 | at | UCLA | 20 | MW | |||
| 12/7/2024 | Penn State | 27 | vs | Oregon | 45 | B10 Championship - Indianapolis IN | ||
| 12/20/2024 | Indiana | 17 | at | Notre Dame | 27 | FBS Playoff round 1 | @ ND | |
| 12/21/2024 | Tennessee | 17 | at | Ohio State | 42 | FBS Playoff round 1 | SEC | |
| SMU | 10 | at | Penn State | 38 | FBS Playoff round 1 | ACC | ||
| 12/26/2024 | Rutgers | vs | Kansas State | Rate Bowl - Phoenix AZ | vs B12 | |||
| 12/27/2024 | Texas A&M | vs | Southern California | Las Vegas Bowl - Las Vegas NV | vs SEC | |||
| 12/28/2024 | Boston College | vs | Nebraska | Pinstripe Bowl - Bronx NY | vs ACC | |||
| 12/30/2024 | Iowa | vs | Missouri | Music City Bowl - Nashville TN | vs SEC | |||
| 12/31/2024 | Penn State | vs | Boise State | FBS Quarterfinal - Fiesta Bowl - Glendale AZ | vs MW | |||
| South Carolina | vs | Illinois | Citrus Bowl - Orlando FL | vs SEC | ||||
| Alabama | vs | Michigan | ReliaQuest Bowl - Tampa FL | vs SEC | ||||
| Louisville | vs | Washington | Sun Bowl - El Paso TX | vs ACC | ||||
| 1/1/2025 | Ohio State | vs | Oregon | FBS Quarterfinal - Rose Bowl - Pasadena CA | ||||
| 1/2/2025 | Minnesota | vs | Virginia Tech | Duke's Mayo Bowl - Charlotte NC | vs ACC |