| 8/29/2024 | Murray State (1-11) | 0 | at | Missouri | 51 | MVC (1AA) | ||
| 9/7/2024 | Buffalo (8-4) | 0 | at | Missouri | 38 | MAC | ||
| 9/14/2024 | Boston College (7-5) | 21 | at | Missouri | 27 | ACC | ||
| 9/21/2024 | Vanderbilt (6-6,3-5) | 27 | at | Missouri | 30 | |||
| 10/5/2024 | Missouri | 10 | at | Texas A&M (8-4,5-3) | 41 | |||
| 10/12/2024 | Missouri | 45 | at | Massachusetts (2-10) | 3 | at Ind | ||
| 10/19/2024 | Auburn (5-7,2-6) | 17 | at | Missouri | 21 | |||
| 10/26/2024 | Missouri | 0 | at | Alabama (9-3,5-3) | 34 | |||
| 11/9/2024 | Oklahoma (6-6,2-6) | 23 | at | Missouri | 30 | |||
| 11/16/2024 | Missouri | 30 | at | South Carolina (9-3,5-3) | 34 | |||
| 11/23/2024 | Missouri | 39 | at | Mississippi State (2-10,0-8) | 20 | |||
| 11/30/2024 | Arkansas (6-6,3-5) | 21 | at | Missouri | 28 | |||
| 12/30/2024 | Iowa (8-4) | vs | Missouri | Music City Bowl - Nashville TN | B10 |
| vs Missouri | vs Other Opponents | Missouri compared to OOs | |
| Record: | 3-9 | 74-70 | |
| Points Scored: | 20.08 | 28.27 | 8.19 |
| Points Allowed: | 29.08 | 25.29 | 3.79 |
| Margin: | -9.00 | 2.98 | 11.98 |
| Total Points: | 49.16 | 53.56 | -4.40 |