| 8/29/2024 | Northern State (6-5) | 3 | at | South Dakota | 45 | NSIC (D2) | ||
| 9/7/2024 | South Dakota | 13 | at | Wisconsin (5-7) | 27 | at B10 | ||
| 9/21/2024 | Drake (8-3) | 3 | at | South Dakota | 42 | Pio | ||
| 9/28/2024 | Southern Illinois (4-8,2-6) | 13 | at | South Dakota | 42 | |||
| 10/5/2024 | South Dakota | 59 | at | Murray State (1-11,0-8) | 0 | |||
| 10/12/2024 | Northern Iowa (3-9,1-7) | 17 | at | South Dakota | 42 | |||
| 10/19/2024 | South Dakota | 27 | at | Youngstown State (4-8,3-5) | 17 | |||
| 10/26/2024 | South Dakota | 17 | at | South Dakota State (12-3,7-2) | 20 | OT | ||
| 11/9/2024 | Indiana State (4-8,3-5) | 0 | at | South Dakota | 49 | |||
| 11/16/2024 | South Dakota | 42 | at | North Dakota (5-7,2-6) | 36 | |||
| 11/23/2024 | North Dakota State (13-2,8-1) | 28 | at | South Dakota | 29 | |||
| 12/14/2024 | UC Davis (11-3) | 21 | at | South Dakota | 35 | FCS Quarterfinal | BSky | |
| 12/21/2024 | South Dakota | 17 | at | Montana State (15-0) | 31 | FCS Semifinal | at BSky |
| vs South Dakota | vs Other Opponents | South Dakota compared to OOs | |
| Record: | 3-10 | 88-64 | |
| Points Scored: | 16.62 | 29.30 | 12.68 |
| Points Allowed: | 35.31 | 25.63 | 9.68 |
| Margin: | -18.69 | 3.67 | 22.36 |
| Total Points: | 51.93 | 54.93 | -3.00 |