| 8/31/2024 | Texas Southern (5-6,4-4) | 27 | at | Prairie View | 9 | |||
| 9/7/2024 | Prairie View | 37 | at | Northwestern State (0-12) | 31 | at SLC | ||
| 9/14/2024 | Prairie View | 0 | at | Michigan State (5-7) | 40 | at B10 | ||
| 9/21/2024 | Southern (8-5,7-3) | 31 | at | Prairie View | 24 | |||
| 9/28/2024 | Grambling (5-7,3-6) | 34 | vs | Prairie View | 36 | Dallas TX | ||
| 10/5/2024 | Prairie View | 28 | at | Incarnate Word (11-3) | 56 | at SLC | ||
| 10/11/2024 | Prairie View | 17 | at | Ark Pine Bluff (3-9,2-6) | 21 | |||
| 10/26/2024 | Texas A&M-Commerce (3-9) | 27 | at | Prairie View | 34 | SLC | ||
| 11/2/2024 | Prairie View | 17 | at | Mississippi Valley State (1-11,1-7) | 16 | |||
| 11/9/2024 | Florida A&M (7-5,5-3) | 12 | at | Prairie View | 31 | |||
| 11/16/2024 | Alcorn State (6-6,5-3) | 26 | at | Prairie View | 13 | |||
| 11/23/2024 | Prairie View | 6 | at | Alabama State (7-5,5-3) | 9 |
| vs Prairie View | vs Other Opponents | Prairie View compared to OOs | |
| Record: | 7-5 | 54-80 | |
| Points Scored: | 27.50 | 21.47 | -6.03 |
| Points Allowed: | 21.00 | 29.95 | -8.95 |
| Margin: | 6.50 | -8.48 | -14.98 |
| Total Points: | 48.50 | 51.42 | -2.92 |