| 9/3/2022 | Lane | 42 | at | Ark Pine Bluff (3-8) | 48 | at SWAC | ||
| 9/10/2022 | Benedict (11-1,10-0) | 14 | at | Lane | 0 | |||
| 9/17/2022 | Clark Atlanta (3-7,3-6) | 6 | at | Lane | 38 | |||
| 9/24/2022 | Edward Waters (4-6,4-4) | 9 | at | Lane | 20 | |||
| 10/1/2022 | Lane | 28 | at | Tennessee State (4-7) | 27 | OT | at OVC | |
| 10/8/2022 | Kentucky State (4-6,4-4) | 31 | at | Lane | 26 | |||
| 10/15/2022 | Lane | 35 | at | Miles (1-9,1-6) | 32 | |||
| 10/22/2022 | Tuskegee (8-3,7-2) | 35 | at | Lane | 31 | |||
| 10/29/2022 | Central State (3-7,2-5) | 31 | at | Lane | 42 | |||
| 11/5/2022 | Lane | 38 | at | Savannah State (5-5,4-4) | 44 |
| vs Lane | vs Other Opponents | Lane compared to OOs | |
| Record: | 5-5 | 41-54 | |
| Points Scored: | 27.70 | 23.55 | -4.15 |
| Points Allowed: | 30.00 | 27.28 | 2.72 |
| Margin: | -2.30 | -3.73 | -1.43 |
| Total Points: | 57.70 | 50.83 | 6.87 |