| 9/3/2022 | Delta State (11-2) | 33 | at | Kentucky State | 10 | GSC | ||
| 9/10/2022 | Kentucky State | 7 | at | Fort Valley State (8-2,7-2) | 9 | |||
| 9/17/2022 | Kentucky State | 3 | at | Dayton (8-3) | 46 | at Pio | ||
| 9/24/2022 | Kentucky State | 14 | at | Benedict (11-1,10-0) | 40 | |||
| 10/2/2022 | Kentucky State | 28 | at | Savannah State (5-5,4-4) | 13 | |||
| 10/8/2022 | Kentucky State | 31 | at | Lane (5-5,4-4) | 26 | |||
| 10/15/2022 | Allen (1-8,0-7) | 22 | at | Kentucky State | 41 | |||
| 10/22/2022 | Kentucky State | 35 | at | Miles (1-9,1-6) | 7 | |||
| 10/29/2022 | Tuskegee (8-3,7-2) | 28 | at | Kentucky State | 7 | |||
| 11/5/2022 | Kentucky State | 30 | at | Central State (3-7,2-5) | 31 |
| vs Kentucky State | vs Other Opponents | Kentucky State compared to OOs | |
| Record: | 6-4 | 55-41 | |
| Points Scored: | 25.50 | 28.81 | 3.31 |
| Points Allowed: | 20.60 | 26.04 | -5.44 |
| Margin: | 4.90 | 2.77 | -2.13 |
| Total Points: | 46.10 | 54.85 | -8.75 |