| 9/3/2022 | Arizona | 38 | at | San Diego State (7-6) | 20 | at MW | ||
| 9/10/2022 | Mississippi State (9-4) | 39 | at | Arizona | 17 | SEC | ||
| 9/17/2022 | North Dakota State (12-3) | 28 | at | Arizona | 31 | MVC (1AA) | ||
| 9/24/2022 | Arizona | 31 | at | California (4-8,2-7) | 49 | |||
| 10/1/2022 | Colorado (1-11,1-8) | 20 | at | Arizona | 43 | |||
| 10/8/2022 | Oregon (10-3,7-2) | 49 | at | Arizona | 22 | |||
| 10/15/2022 | Arizona | 39 | at | Washington (11-2,7-2) | 49 | |||
| 10/29/2022 | Southern California (11-3,8-2) | 45 | at | Arizona | 37 | |||
| 11/5/2022 | Arizona | 20 | at | Utah (10-4,8-2) | 45 | |||
| 11/12/2022 | Arizona | 34 | at | UCLA (9-4,6-3) | 28 | |||
| 11/19/2022 | Washington State (7-6,4-5) | 31 | at | Arizona | 20 | |||
| 11/25/2022 | Arizona State (3-9,2-7) | 35 | at | Arizona | 38 |
| vs Arizona | vs Other Opponents | Arizona compared to OOs | |
| Record: | 7-5 | 87-58 | |
| Points Scored: | 36.50 | 31.32 | -5.18 |
| Points Allowed: | 30.83 | 26.35 | 4.48 |
| Margin: | 5.67 | 4.97 | -0.70 |
| Total Points: | 67.33 | 57.67 | 9.66 |