| 9/11/2021 | Carroll WI | 35 | at | Ill. Benedictine (8-2) | 24 | at NAC | ||
| 9/18/2021 | Illinois Wesleyan (3-7,3-6) | 33 | at | Carroll WI | 34 | |||
| 9/25/2021 | Carroll WI | 25 | at | Millikin (3-7,3-6) | 32 | |||
| 10/2/2021 | North Central (13-1,9-0) | 62 | at | Carroll WI | 7 | |||
| 10/9/2021 | Carroll WI | 34 | at | North Park (2-8,2-7) | 26 | |||
| 10/16/2021 | Wheaton (10-2,8-1) | 48 | at | Carroll WI | 13 | |||
| 10/23/2021 | Carroll WI | 29 | at | Augustana IL (5-5,4-5) | 26 | |||
| 10/30/2021 | Carroll WI | 12 | at | Washington U (7-4,7-2) | 35 | |||
| 11/6/2021 | Carthage (3-7,3-6) | 17 | at | Carroll WI | 26 | |||
| 11/13/2021 | Carroll WI | 30 | at | Elmhurst (1-9,1-8) | 28 |
| vs Carroll WI | vs Other Opponents | Carroll WI compared to OOs | |
| Record: | 4-6 | 51-46 | |
| Points Scored: | 33.10 | 30.94 | -2.16 |
| Points Allowed: | 24.50 | 30.03 | -5.53 |
| Margin: | 8.60 | 0.91 | -7.69 |
| Total Points: | 57.60 | 60.97 | -3.37 |