| 8/31/2019 | Missouri (6-6) | 31 | at | Wyoming | 37 | SEC | ||
| 9/7/2019 | Wyoming | 23 | at | Texas State (3-9) | 14 | at SBC | ||
| 9/14/2019 | Idaho (5-7) | 16 | at | Wyoming | 21 | BSky (1AA) | ||
| 9/21/2019 | Wyoming | 21 | at | Tulsa (4-8) | 24 | at AAC | ||
| 9/28/2019 | UNLV (4-8,2-6) | 17 | at | Wyoming | 53 | |||
| 10/12/2019 | Wyoming | 22 | at | San Diego State (10-3,5-3) | 26 | |||
| 10/19/2019 | New Mexico (2-10,0-8) | 10 | at | Wyoming | 23 | |||
| 10/26/2019 | Nevada (7-6,4-4) | 3 | at | Wyoming | 31 | |||
| 11/9/2019 | Wyoming | 17 | at | Boise State (12-2,9-0) | 20 | OT | ||
| 11/16/2019 | Wyoming | 21 | at | Utah State (7-6,6-2) | 26 | |||
| 11/22/2019 | Colorado State (4-8,3-5) | 7 | at | Wyoming | 17 | |||
| 11/30/2019 | Wyoming | 6 | at | Air Force (11-2,7-1) | 20 | |||
| 12/31/2019 | Wyoming | 38 | vs | Georgia State (7-6) | 17 | Arizona Bowl - Phoenix AZ | vs SBC |
| vs Wyoming | vs Other Opponents | Wyoming compared to OOs | |
| Record: | 5-8 | 77-73 | |
| Points Scored: | 17.77 | 27.21 | 9.44 |
| Points Allowed: | 25.38 | 28.71 | -3.33 |
| Margin: | -7.61 | -1.50 | 6.11 |
| Total Points: | 43.15 | 55.92 | -12.77 |