| 8/31/2019 | Louisiana Tech | 14 | at | Texas (8-5) | 45 | at B12 | ||
| 9/7/2019 | Grambling (6-5) | 14 | at | Louisiana Tech | 20 | SWAC (1AA) | ||
| 9/14/2019 | Louisiana Tech | 35 | at | Bowling Green (3-9) | 7 | at MAC | ||
| 9/20/2019 | Florida Intl (6-7,3-5) | 31 | at | Louisiana Tech | 43 | |||
| 9/28/2019 | Louisiana Tech | 23 | at | Rice (3-9,3-5) | 20 | OT | ||
| 10/12/2019 | Massachusetts (1-11) | 21 | at | Louisiana Tech | 69 | Ind | ||
| 10/19/2019 | Southern Miss (7-6,5-3) | 30 | at | Louisiana Tech | 45 | |||
| 10/26/2019 | Louisiana Tech | 42 | at | UTEP (1-11,0-8) | 21 | |||
| 11/9/2019 | North Texas (4-8,3-5) | 17 | at | Louisiana Tech | 52 | |||
| 11/15/2019 | Louisiana Tech | 10 | at | Marshall (8-5,6-2) | 31 | |||
| 11/23/2019 | Louisiana Tech | 14 | at | UAB (9-5,6-3) | 20 | |||
| 11/30/2019 | Texas-San Antonio (4-8,3-5) | 27 | at | Louisiana Tech | 41 | |||
| 12/26/2019 | Louisiana Tech | 14 | vs | Miami-Florida (6-7) | 0 | Independence Bowl - Shreveport LA | vs ACC |
| vs Louisiana Tech | vs Other Opponents | Louisiana Tech compared to OOs | |
| Record: | 3-10 | 63-86 | |
| Points Scored: | 21.85 | 24.66 | 2.81 |
| Points Allowed: | 32.46 | 29.53 | 2.93 |
| Margin: | -10.61 | -4.87 | 5.74 |
| Total Points: | 54.31 | 54.19 | 0.12 |