| 8/30/2019 | Massachusetts | 21 | at | Rutgers (2-10) | 48 | at B10 | ||
| 9/7/2019 | Southern Illinois (7-5) | 45 | at | Massachusetts | 20 | MVC (1AA) | ||
| 9/14/2019 | Massachusetts | 17 | at | UNC-Charlotte (7-6) | 52 | at CUSA | ||
| 9/21/2019 | Coastal Carolina (5-7) | 62 | at | Massachusetts | 28 | SBC | ||
| 9/28/2019 | Akron (0-12) | 29 | at | Massachusetts | 37 | MAC | ||
| 10/5/2019 | Massachusetts | 0 | at | Florida Intl (6-7) | 44 | at CUSA | ||
| 10/12/2019 | Massachusetts | 21 | at | Louisiana Tech (10-3) | 69 | at CUSA | ||
| 10/26/2019 | Connecticut (2-10) | 56 | at | Massachusetts | 35 | AAC | ||
| 11/2/2019 | Liberty (8-5,3-1) | 63 | at | Massachusetts | 21 | |||
| 11/9/2019 | Massachusetts | 7 | at | Army (5-8,1-0) | 63 | |||
| 11/16/2019 | Massachusetts | 6 | at | Northwestern (3-9) | 45 | at B10 | ||
| 11/23/2019 | BYU (7-6,2-0) | 56 | at | Massachusetts | 24 |
| vs Massachusetts | vs Other Opponents | Massachusetts compared to OOs | |
| Record: | 11-1 | 51-87 | |
| Points Scored: | 52.67 | 22.46 | -30.21 |
| Points Allowed: | 19.75 | 29.73 | -9.98 |
| Margin: | 32.92 | -7.27 | -40.19 |
| Total Points: | 72.42 | 52.19 | 20.23 |