| 9/1/2018 | South Dakota State | at | Iowa State (8-5) | CCD | at B12 | |||
| 9/8/2018 | Montana State (8-5) | 14 | at | South Dakota State | 45 | BSky | ||
| 9/15/2018 | Ark Pine Bluff (2-9) | 6 | at | South Dakota State | 90 | SWAC | ||
| 9/29/2018 | South Dakota State | 17 | at | North Dakota State (15-0,9-0) | 21 | |||
| 10/6/2018 | Indiana State (7-4,5-3) | 51 | at | South Dakota State | 54 | OT | ||
| 10/13/2018 | Youngstown State (4-7,3-5) | 7 | at | South Dakota State | 36 | |||
| 10/20/2018 | South Dakota State | 9 | at | Northern Iowa (7-6,5-3) | 24 | |||
| 10/27/2018 | South Dakota State | 38 | at | Illinois State (6-5,3-5) | 28 | |||
| 11/3/2018 | Missouri State (4-7,2-6) | 7 | at | South Dakota State | 59 | |||
| 11/10/2018 | South Dakota State | 57 | at | Southern Illinois (2-9,1-7) | 38 | |||
| 11/17/2018 | South Dakota (4-7,3-5) | 27 | at | South Dakota State | 49 | |||
| 12/1/2018 | Duquesne (9-4) | 6 | at | South Dakota State | 51 | 1AA Playoff Round 2 | NE | |
| 12/8/2018 | South Dakota State | 27 | at | Kennesaw St (11-2) | 17 | 1AA Playoff Quarterfinal | at BigS | |
| 12/14/2018 | South Dakota State | 21 | at | North Dakota State (15-0,9-0) | 44 | 1AA Semifinal |
| vs South Dakota State | vs Other Opponents | South Dakota State compared to OOs | |
| Record: | 3-10 | 97-60 | |
| Points Scored: | 22.31 | 32.22 | 9.91 |
| Points Allowed: | 42.54 | 24.57 | 17.97 |
| Margin: | -20.23 | 7.65 | 27.88 |
| Total Points: | 64.85 | 56.79 | 8.06 |