| 9/1/2018 | St Xavier (9-4) | 0 | at | Illinois State | 46 | MSFA (NAIA) | ||
| 9/8/2018 | Eastern Illinois (3-8) | 10 | at | Illinois State | 48 | OVC | ||
| 9/22/2018 | Illinois State | 35 | at | Colorado State (3-9) | 19 | at MW | ||
| 9/29/2018 | Illinois State | 21 | at | Missouri State (4-7,2-6) | 24 | |||
| 10/6/2018 | Western Illinois (5-6,4-4) | 16 | at | Illinois State | 33 | |||
| 10/13/2018 | Southern Illinois (2-9,1-7) | 3 | at | Illinois State | 51 | |||
| 10/20/2018 | Illinois State | 14 | at | North Dakota State (15-0,9-0) | 28 | |||
| 10/27/2018 | South Dakota State (10-3,6-3) | 38 | at | Illinois State | 28 | |||
| 11/3/2018 | Illinois State | 16 | at | Northern Iowa (7-6,5-3) | 26 | |||
| 11/10/2018 | Illinois State | 23 | at | Indiana State (7-4,5-3) | 28 | |||
| 11/17/2018 | Youngstown State (4-7,3-5) | 28 | at | Illinois State | 35 |
| vs Illinois State | vs Other Opponents | Illinois State compared to OOs | |
| Record: | 5-6 | 64-57 | |
| Points Scored: | 20.00 | 31.10 | 11.10 |
| Points Allowed: | 31.82 | 28.00 | 3.82 |
| Margin: | -11.82 | 3.10 | 14.92 |
| Total Points: | 51.82 | 59.10 | -7.28 |