| 9/1/2018 | Southern (7-4) | 7 | at | TCU | 55 | SWAC (1AA) | ||
| 9/7/2018 | TCU | 42 | at | SMU (5-7) | 12 | at AAC | ||
| 9/15/2018 | Ohio State (13-1) | 40 | vs | TCU | 28 | Arlington TX | B10 | |
| 9/22/2018 | TCU | 16 | at | Texas (10-4,7-3) | 31 | |||
| 9/29/2018 | Iowa State (8-5,6-3) | 14 | at | TCU | 17 | |||
| 10/11/2018 | Texas Tech (5-7,3-6) | 17 | at | TCU | 14 | |||
| 10/20/2018 | Oklahoma (12-2,9-1) | 52 | at | TCU | 27 | |||
| 10/27/2018 | TCU | 26 | at | Kansas (3-9,1-8) | 27 | |||
| 11/3/2018 | Kansas State (5-7,3-6) | 13 | at | TCU | 14 | |||
| 11/10/2018 | TCU | 10 | at | West Virginia (8-4,6-3) | 47 | |||
| 11/17/2018 | TCU | 16 | at | Baylor (7-6,4-5) | 9 | |||
| 11/24/2018 | Oklahoma State (7-6,3-6) | 24 | at | TCU | 31 | |||
| 12/26/2018 | California (7-6) | 7 | vs | TCU | 10 | OT | CHEEZ-IT BOWL - Phoenix AZ | P12 |
| vs TCU | vs Other Opponents | TCU compared to OOs | |
| Record: | 6-7 | 91-61 | |
| Points Scored: | 23.08 | 33.41 | 10.33 |
| Points Allowed: | 23.54 | 28.55 | -5.01 |
| Margin: | -0.46 | 4.86 | 5.32 |
| Total Points: | 46.62 | 61.96 | -15.34 |