| 8/31/2018 | Syracuse | 55 | at | Western Michigan (7-6) | 42 | at MAC | ||
| 9/8/2018 | Wagner (4-7) | 10 | at | Syracuse | 62 | NE (1AA) | ||
| 9/15/2018 | Florida State (5-7,3-5) | 7 | at | Syracuse | 30 | |||
| 9/22/2018 | Connecticut (1-11) | 21 | at | Syracuse | 51 | AAC | ||
| 9/29/2018 | Syracuse | 23 | at | Clemson (15-0,9-0) | 27 | |||
| 10/6/2018 | Syracuse | 37 | at | Pittsburgh (7-7,6-3) | 44 | OT | ||
| 10/20/2018 | North Carolina (2-9,1-7) | 37 | at | Syracuse | 40 | 2OT | ||
| 10/27/2018 | North Carolina State (9-4,5-3) | 41 | at | Syracuse | 51 | |||
| 11/3/2018 | Syracuse | 41 | at | Wake Forest (7-6,3-5) | 24 | |||
| 11/9/2018 | Louisville (2-10,0-8) | 23 | at | Syracuse | 54 | |||
| 11/17/2018 | Syracuse | 3 | vs | Notre Dame (12-1) | 36 | Bronx NY | vs ND | |
| 11/24/2018 | Syracuse | 42 | at | Boston College (7-5,4-4) | 21 | |||
| 12/28/2018 | West Virginia (8-4) | 18 | vs | Syracuse | 34 | CAMPING WORLD BOWL - Orlando FL | B12 |
| vs Syracuse | vs Other Opponents | Syracuse compared to OOs | |
| Record: | 3-10 | 83-67 | |
| Points Scored: | 27.00 | 30.70 | 3.70 |
| Points Allowed: | 40.23 | 29.79 | 10.44 |
| Margin: | -13.23 | 0.91 | 14.14 |
| Total Points: | 67.23 | 60.49 | 6.74 |