| 9/1/2018 | Michigan (10-3) | 17 | at | Notre Dame | 24 | B10 | ||
| 9/8/2018 | Ball State (4-8) | 16 | at | Notre Dame | 24 | MAC | ||
| 9/15/2018 | Vanderbilt (6-7) | 17 | at | Notre Dame | 22 | SEC | ||
| 9/22/2018 | Notre Dame | 56 | at | Wake Forest (7-6) | 27 | at ACC | ||
| 9/29/2018 | Stanford (9-4) | 17 | at | Notre Dame | 38 | P12 | ||
| 10/6/2018 | Notre Dame | 45 | at | Virginia Tech (6-7) | 23 | at ACC | ||
| 10/13/2018 | Pittsburgh (7-7) | 14 | at | Notre Dame | 19 | ACC | ||
| 10/27/2018 | Navy (3-10) | 22 | vs | Notre Dame | 44 | San Diego CA | AAC | |
| 11/3/2018 | Notre Dame | 31 | at | Northwestern (9-5) | 21 | at B10 | ||
| 11/10/2018 | Florida State (5-7) | 13 | at | Notre Dame | 42 | ACC | ||
| 11/17/2018 | Syracuse (10-3) | 3 | vs | Notre Dame | 36 | Bronx NY | ACC | |
| 11/24/2018 | Notre Dame | 24 | at | Southern California (5-7) | 17 | at P12 | ||
| 12/29/2018 | Notre Dame | 3 | vs | Clemson (15-0) | 30 | 1A Semifinal Arlington TX | vs ACC |
| vs Notre Dame | vs Other Opponents | Notre Dame compared to OOs | |
| Record: | 1-12 | 95-62 | |
| Points Scored: | 18.23 | 30.89 | 12.66 |
| Points Allowed: | 31.38 | 26.20 | 5.18 |
| Margin: | -13.15 | 4.69 | 17.84 |
| Total Points: | 49.61 | 57.09 | -7.48 |