| 9/1/2018 | Kent State (2-10) | 24 | at | Illinois | 31 | MAC | ||
| 9/8/2018 | Western Illinois (5-6) | 14 | at | Illinois | 34 | MVC (1AA) | ||
| 9/15/2018 | South Florida (7-6) | 25 | vs | Illinois | 19 | Chicago IL | AAC | |
| 9/21/2018 | Penn State (9-4,6-3) | 63 | at | Illinois | 24 | |||
| 10/6/2018 | Illinois | 38 | at | Rutgers (1-11,0-9) | 17 | |||
| 10/13/2018 | Purdue (6-7,5-4) | 46 | at | Illinois | 7 | |||
| 10/20/2018 | Illinois | 20 | at | Wisconsin (8-5,5-4) | 49 | |||
| 10/27/2018 | Illinois | 33 | at | Maryland (5-7,3-6) | 63 | |||
| 11/3/2018 | Minnesota (7-6,3-6) | 31 | at | Illinois | 55 | |||
| 11/10/2018 | Illinois | 35 | at | Nebraska (4-8,3-6) | 54 | |||
| 11/17/2018 | Iowa (9-4,5-4) | 63 | at | Illinois | 0 | |||
| 11/24/2018 | Illinois | 16 | at | Northwestern (9-5,8-2) | 24 |
| vs Illinois | vs Other Opponents | Illinois compared to OOs | |
| Record: | 8-4 | 64-75 | |
| Points Scored: | 39.42 | 26.28 | -13.14 |
| Points Allowed: | 26.00 | 27.25 | -1.25 |
| Margin: | 13.42 | -0.97 | -14.39 |
| Total Points: | 65.42 | 53.53 | 11.89 |