| 9/1/2018 | Central Michigan | 20 | at | Kentucky (10-3) | 35 | at SEC | ||
| 9/8/2018 | Kansas (3-9) | 31 | at | Central Michigan | 7 | B12 | ||
| 9/15/2018 | Central Michigan | 16 | at | Northern Illinois (8-6,7-2) | 24 | |||
| 9/22/2018 | Maine (10-4) | 5 | at | Central Michigan | 17 | CAAF (1AA) | ||
| 9/29/2018 | Central Michigan | 20 | at | Michigan State (7-6) | 31 | at B10 | ||
| 10/6/2018 | Buffalo (10-4,7-2) | 34 | at | Central Michigan | 24 | |||
| 10/13/2018 | Ball State (4-8,3-5) | 24 | at | Central Michigan | 23 | |||
| 10/20/2018 | Western Michigan (7-6,5-3) | 35 | at | Central Michigan | 10 | |||
| 10/27/2018 | Central Michigan | 10 | at | Akron (4-8,2-6) | 17 | |||
| 11/3/2018 | Central Michigan | 7 | at | Eastern Michigan (7-6,5-3) | 17 | |||
| 11/10/2018 | Bowling Green (3-9,2-6) | 24 | at | Central Michigan | 13 | |||
| 11/23/2018 | Central Michigan | 13 | at | Toledo (7-6,5-3) | 51 |
| vs Central Michigan | vs Other Opponents | Central Michigan compared to OOs | |
| Record: | 11-1 | 69-74 | |
| Points Scored: | 27.33 | 26.54 | -0.79 |
| Points Allowed: | 15.00 | 27.67 | -12.67 |
| Margin: | 12.33 | -1.13 | -13.46 |
| Total Points: | 42.33 | 54.21 | -11.88 |