| 8/31/2018 | Monmouth NJ (8-3) | 17 | at | Eastern Michigan | 51 | BigS (1AA) | ||
| 9/8/2018 | Eastern Michigan | 20 | at | Purdue (6-7) | 19 | at B10 | ||
| 9/15/2018 | Eastern Michigan | 28 | at | Buffalo (10-4,7-2) | 35 | |||
| 9/22/2018 | Eastern Michigan | 20 | at | San Diego State (7-6) | 23 | OT | at MW | |
| 9/29/2018 | Northern Illinois (8-6,7-2) | 26 | at | Eastern Michigan | 23 | 3OT | ||
| 10/6/2018 | Eastern Michigan | 24 | at | Western Michigan (7-6,5-3) | 27 | |||
| 10/13/2018 | Toledo (7-6,5-3) | 26 | at | Eastern Michigan | 28 | |||
| 10/20/2018 | Eastern Michigan | 42 | at | Ball State (4-8,3-5) | 20 | |||
| 10/27/2018 | Army (11-2) | 37 | at | Eastern Michigan | 22 | Ind | ||
| 11/3/2018 | Central Michigan (1-11,0-8) | 7 | at | Eastern Michigan | 17 | |||
| 11/10/2018 | Akron (4-8,2-6) | 7 | at | Eastern Michigan | 27 | |||
| 11/23/2018 | Eastern Michigan | 28 | at | Kent State (2-10,1-7) | 20 | |||
| 12/15/2018 | Georgia Southern (10-3) | 23 | vs | Eastern Michigan | 21 | RAYCOM MEDIA CAMELLIA BOWL - Montgomery AL | SBC |
| vs Eastern Michigan | vs Other Opponents | Eastern Michigan compared to OOs | |
| Record: | 6-7 | 79-73 | |
| Points Scored: | 22.08 | 28.00 | 5.92 |
| Points Allowed: | 27.00 | 27.59 | -0.59 |
| Margin: | -4.92 | 0.41 | 5.33 |
| Total Points: | 49.08 | 55.59 | -6.51 |