| 9/2/2017 | Butler (6-5) | 0 | at | Illinois State | 45 | Pio | ||
| 9/16/2017 | Illinois State | 44 | at | Eastern Illinois (6-5) | 13 | at OVC | ||
| 9/23/2017 | Illinois State | 34 | at | Missouri State (3-8,2-6) | 9 | |||
| 9/30/2017 | Indiana State (0-11,0-8) | 13 | at | Illinois State | 24 | |||
| 10/7/2017 | Illinois State | 16 | at | Northern Arizona (7-5) | 37 | at BSky | ||
| 10/14/2017 | Illinois State | 7 | at | Southern Illinois (4-7,2-6) | 42 | |||
| 10/21/2017 | South Dakota (8-5,4-4) | 21 | at | Illinois State | 37 | |||
| 10/28/2017 | Illinois State | 35 | at | Youngstown State (6-5,4-4) | 0 | |||
| 11/4/2017 | Western Illinois (8-4,5-3) | 31 | at | Illinois State | 14 | |||
| 11/11/2017 | Illinois State | 24 | at | South Dakota State (11-3,7-2) | 27 | OT | ||
| 11/18/2017 | North Dakota State (14-1,7-1) | 20 | at | Illinois State | 7 |
| vs Illinois State | vs Other Opponents | Illinois State compared to OOs | |
| Record: | 5-6 | 68-53 | |
| Points Scored: | 19.36 | 30.56 | 11.20 |
| Points Allowed: | 26.09 | 26.25 | -0.16 |
| Margin: | -6.73 | 4.31 | 11.04 |
| Total Points: | 45.45 | 56.81 | -11.36 |