| 9/3/2016 | Apprentice (4-3) | 20 | at | Methodist | 24 | D3Ind | ||
| 9/10/2016 | Methodist | 32 | at | Guilford (4-6) | 47 | at ODC | ||
| 9/17/2016 | Methodist | 16 | at | Randolph-Macon (9-2) | 34 | at ODC | ||
| 10/1/2016 | Maryville (8-2,6-1) | 52 | at | Methodist | 13 | |||
| 10/9/2016 | Methodist | at | Averett (5-5,4-3) | PPD | ||||
| 10/15/2016 | Methodist | vs | North Carolina Wesleyan (5-4,4-2) | Cancelled WX | ||||
| 10/22/2016 | Huntingdon AL (9-2,6-1) | 47 | at | Methodist | 14 | |||
| 10/29/2016 | Methodist | 30 | at | Ferrum (6-4,4-3) | 35 | |||
| 11/5/2016 | Greensboro (1-9,0-7) | 6 | at | Methodist | 38 | |||
| 11/12/2016 | Methodist | 43 | at | LaGrange (3-7,1-6) | 26 | |||
| 11/19/2016 | Averett (5-5,4-3) | 28 | at | Methodist | 14 |
| vs Methodist | vs Other Opponents | Methodist compared to OOs | |
| Record: | 6-3 | 52-46 | |
| Points Scored: | 32.78 | 31.01 | -1.77 |
| Points Allowed: | 24.89 | 29.11 | -4.22 |
| Margin: | 7.89 | 1.90 | -5.99 |
| Total Points: | 57.67 | 60.12 | -2.45 |