| 9/3/2016 | Maryville | 33 | at | Berry (9-1) | 34 | at SAA | ||
| 9/10/2016 | Maryville | 38 | at | Hanover (4-6) | 0 | at HCA | ||
| 9/17/2016 | Emory & Henry (6-4) | 36 | at | Maryville | 43 | ODC | ||
| 10/1/2016 | Maryville | 52 | at | Methodist (3-6,2-4) | 13 | |||
| 10/8/2016 | North Carolina Wesleyan (5-4,4-2) | 17 | at | Maryville | 31 | |||
| 10/15/2016 | Maryville | 42 | at | Ferrum (6-4,4-3) | 19 | |||
| 10/22/2016 | Averett (5-5,4-3) | 26 | at | Maryville | 31 | |||
| 10/29/2016 | Maryville | 30 | at | LaGrange (3-7,1-6) | 19 | |||
| 11/5/2016 | Huntingdon AL (9-2,6-1) | 28 | at | Maryville | 24 | |||
| 11/12/2016 | Maryville | 70 | at | Greensboro (1-9,0-7) | 14 |
| vs Maryville | vs Other Opponents | Maryville compared to OOs | |
| Record: | 2-8 | 49-40 | |
| Points Scored: | 20.60 | 30.45 | 9.85 |
| Points Allowed: | 39.40 | 29.70 | 9.70 |
| Margin: | -18.80 | 0.75 | 19.55 |
| Total Points: | 60.00 | 60.15 | -0.15 |