| 9/3/2016 | Seton Hill | 50 | at | Bowie State (7-4) | 48 | at CIAA | ||
| 9/10/2016 | Seton Hill | 38 | at | Millersville (2-9,1-9) | 24 | |||
| 9/17/2016 | Kutztown (7-4,7-3) | 22 | at | Seton Hill | 44 | |||
| 9/24/2016 | California PA (11-1,11-0) | 59 | at | Seton Hill | 17 | |||
| 10/1/2016 | Seton Hill | 39 | at | Indiana PA (10-2,9-2) | 47 | |||
| 10/8/2016 | Clarion (4-7,4-7) | 23 | at | Seton Hill | 27 | |||
| 10/15/2016 | Seton Hill | 12 | at | Gannon (5-6,4-6) | 34 | |||
| 10/22/2016 | Mercyhurst (3-8,3-7) | 45 | at | Seton Hill | 55 | |||
| 10/29/2016 | Seton Hill | 34 | at | Edinboro (9-2,8-2) | 42 | |||
| 11/5/2016 | Seton Hill | 21 | at | Slippery Rock (7-4,6-4) | 33 | |||
| 11/12/2016 | Shippensburg (7-4,6-4) | 30 | at | Seton Hill | 21 |
| vs Seton Hill | vs Other Opponents | Seton Hill compared to OOs | |
| Record: | 6-5 | 66-46 | |
| Points Scored: | 37.00 | 33.03 | -3.97 |
| Points Allowed: | 32.55 | 27.23 | 5.32 |
| Margin: | 4.45 | 5.80 | 1.35 |
| Total Points: | 69.55 | 60.26 | 9.29 |