| 9/1/2016 | Mercyhurst | 0 | at | Ashland (9-2) | 48 | at GLIAC | ||
| 9/10/2016 | Mercyhurst | 23 | at | Kutztown (7-4,7-3) | 19 | |||
| 9/17/2016 | East Stroudsburg (4-7,3-7) | 34 | at | Mercyhurst | 31 | |||
| 9/24/2016 | Clarion (4-7,4-7) | 35 | at | Mercyhurst | 34 | |||
| 10/1/2016 | Mercyhurst | 38 | at | Gannon (5-6,4-6) | 35 | OT | ||
| 10/8/2016 | Mercyhurst | 25 | at | Slippery Rock (7-4,6-4) | 37 | |||
| 10/15/2016 | Edinboro (9-2,8-2) | 45 | at | Mercyhurst | 16 | |||
| 10/22/2016 | Mercyhurst | 45 | at | Seton Hill (5-6,4-6) | 55 | |||
| 10/29/2016 | California PA (11-1,11-0) | 55 | at | Mercyhurst | 14 | |||
| 11/5/2016 | Mercyhurst | 20 | at | Indiana PA (10-2,9-2) | 31 | |||
| 11/12/2016 | Lock Haven (4-7,4-7) | 14 | at | Mercyhurst | 49 |
| vs Mercyhurst | vs Other Opponents | Mercyhurst compared to OOs | |
| Record: | 8-3 | 67-45 | |
| Points Scored: | 37.09 | 35.09 | -2.00 |
| Points Allowed: | 26.82 | 29.13 | -2.31 |
| Margin: | 10.27 | 5.96 | -4.31 |
| Total Points: | 63.91 | 64.22 | -0.31 |