| 9/1/2016 | Pace (0-11) | 7 | at | Millersville | 28 | NE10 | ||
| 9/10/2016 | Seton Hill (5-6,4-6) | 38 | at | Millersville | 24 | |||
| 9/17/2016 | Millersville | 0 | at | California PA (11-1,11-0) | 61 | |||
| 9/24/2016 | Kutztown (7-4,7-3) | 41 | at | Millersville | 13 | |||
| 10/1/2016 | Millersville | 15 | at | Bloomsburg (6-5,5-5) | 29 | |||
| 10/8/2016 | East Stroudsburg (4-7,3-7) | 38 | at | Millersville | 23 | |||
| 10/15/2016 | Millersville | 17 | at | Lock Haven (4-7,4-7) | 29 | |||
| 10/22/2016 | Shippensburg (7-4,6-4) | 43 | at | Millersville | 9 | |||
| 10/29/2016 | Millersville | 34 | at | Cheyney (1-10,0-10) | 6 | |||
| 11/5/2016 | Millersville | 0 | at | West Chester (8-3,7-3) | 52 | |||
| 11/12/2016 | Millersville | 14 | at | Gannon (5-6,4-6) | 31 |
| vs Millersville | vs Other Opponents | Millersville compared to OOs | |
| Record: | 9-2 | 49-62 | |
| Points Scored: | 34.09 | 27.72 | -6.37 |
| Points Allowed: | 16.09 | 31.01 | -14.92 |
| Margin: | 18.00 | -3.29 | -21.29 |
| Total Points: | 50.18 | 58.73 | -8.55 |